SARMs were first developed at the University Of Arizona College Of Medicine by Dr. David Kalman and his team under a grant from the National Institute of Health, The National Center for Research Resources, and The National Institute of Arthritis and Musculoskeletal Skin Diseases. In this article, we’ll discuss the history of SARMs, their mechanism of action, common misconceptions about them, and how they can be used to increase muscle mass.
Defining what SARMs are
SARMs or also known as Selective Androgen Receptor Modulators are a type of drug that mimics the effects of testosterone on muscle growth, strength gains, bone density, and other similar effects. However unlike traditional steroids which cause negative side effects such as hair loss, acne issues, and balding they do not have those side effects and provide an alternative to these traditional performance enhancers. Unlike steroids and prohormones, they do not shut down your body’s natural testosterone-producing abilities which is why they’re an attractive option to others.
History of SARMs
What are SARMs? They were first developed at the University Of Arizona College Of Medicine by Dr. David Kalman and his team under a grant from the National Institute of Health, The National Center for Research Resources, and The National Institute of Arthritis and Musculoskeletal Skin Diseases. In this article, we’ll discuss the history of SARMs, their mechanism of action, common misconceptions about them, and how they can be used to increase muscle mass.
Their research began in the 1990s when scientists were researching a possible treatment for osteoporosis. In clinical trials, it was discovered that SARMs caused an anabolic effect on bone tissue while having no effect on muscles which led them to believe that they could be used as a possible treatment for osteoporosis. However, during this clinical trial, they observed an effect on muscle tissue which led them to start researching SARMs as potential treatments for muscle-wasting diseases such as cancer and AIDS.
How SARMs work inside the body?
At their core, SARMs work by selectively activating certain androgen receptors in your muscle cells that respond to specific hormones like testosterone, dihydrotestosterone, etc. They are also increasingly being used off-label for therapeutic purposes in medicine for several different conditions including muscle wasting diseases, osteoporosis, and even some forms of cancer due to their selective nature in targeting certain receptors in the body.
SARMs are selective in their ability to modulate androgen receptors because they only have what’s known as agonist properties which makes them different from traditional steroids. An agonist is simply a substance that binds to a receptor in the body triggering a certain effect, in this case, muscle growth. However, anabolic steroids are both anabolic and androgenic which means they bind to both androgen and anabolic receptors causing the body to shut down its own natural production of testosterone. This is why steroids like test and Dianabol can cause side effects such as hair loss, acne issues, and shutdown of the hypothalamic-pituitary axis (HPTA) because those compounds have agonist properties that activate both androgen and anabolic receptors which leads to a negative feedback loop where your body shuts down its own natural production of testosterone.
SARMs on the other hand only have agonist properties on some specific androgen receptors in certain muscles which means they can be selectively targeted to cause positive effects on some tissues without causing those side effects in others.
What are SARMs used for?
SARMs are used for several different reasons today. One of the most common ways they’re being used is as a replacement to steroids and prohormones in sports by athletes looking for performance-enhancing drugs that will give them good results without the negative side effects. This has been banned by every major sporting organization around the world including MLB, the NFL, NCAA, Olympics, and several others.
Another common use for SARMs is as medical treatments. Several different studies show that they can increase muscle mass in healthy individuals as well as those who suffer from diseases such as cancer and AIDS due to their ability to selectively target only certain muscles. They’ve been used both clinically and off-label for several different medical conditions.
Finally, SARMs are used medically to help improve body composition in patients with muscle wasting diseases like cancer and AIDS because of their ability to selectively target certain muscles while limiting the potential side effects on other tissues. This results in more muscle gains with less fat storage which is why they’re seen as a promising treatment option moving forward.
Can a beginner use SARMs?
Yes, it is possible for beginners to use SARMs because they are all considered selective which means you do not need a PCT plan when taking them on your own. However, it is always recommended to have a PCT plan in place just in case you experience any issues like testosterone suppression.
In most cases, you will only need to take a PCT plan after you use SARMs for about 12 weeks. The reason for this is because it typically takes that long before the benefits start to diminish and you begin experiencing side effects like low testosterone and estrogen problems.
What are the Benefits of SARMs?
The biggest benefit you’ll find with different types of SARMs is that they’re very selective in their nature which means you can target specific muscle groups without running into many of the side effects associated with steroids and prohormones. They also provide some great potential medical benefits for several different kinds of conditions.
One common benefit with SARMs is that they help enhance the lean body mass in patients suffering from muscle wasting diseases like cancer and AIDS because they can activate certain receptors involved in cell metabolism which leads to an increase in muscle gains without many of the side effects that are seen commonly with other treatments for those conditions.
SARMs are also commonly used by athletes and bodybuilders looking to enhance performance and muscle gains without running into many of the side effects that come with other types of treatments.
The positive effects of using SARMs
SARMs are typically known for three main positive effects. The first positive effect is that they help increase lean body mass in patients suffering from muscle wasting diseases like cancer and AIDS because they can activate certain receptors involved in cell metabolism which leads to an increase in muscle gains without many of the side effects that are seen commonly with other treatments for those conditions.
Secondly, SARMs are commonly used by athletes and bodybuilders looking to enhance performance and muscle gains without running into many of the side effects that come with other types of treatments. This is especially true for those who want to use them as part of a cutting cycle to lose fat while keeping as much lean tissue as possible.
The final main positive effect of SARMs is that they help enhance the effectiveness of other treatments for muscle-wasting diseases like cancer and AIDS because they can selectively target groups of muscles without causing any negative effects on other tissues.
What are the side effects of using SARMs?
The main side effect that will happen with most types of SARMs is it will suppress testosterone production in men which means they’ll need to make sure they’re using an AI (aromatase inhibitor) or testosterone replacement therapy if they don’t want to lose gains.
On top of that, SARMs can be very tough on your liver so you’ll want to watch out for any symptoms associated with damage like jaundice, nausea and vomiting, light or clay-colored bowel movements, and stomach pain.
The final potential side effect that may occur is SARMs can cause acne to flare up on the skin which means you’ll want to make sure your skincare routine is on point so you can avoid any breakouts.
The proper dosage instructions for SARMs
The recommended dosage for SARMs will depend on a variety of different factors including age, gender, and body weight. For example, women typically need a lower dose than men because the effects are stronger in male patients.
In addition to that, younger patients usually have a lower tolerance for medications so you’ll want to stick with a smaller dose compared to older patients who can benefit from higher doses to get better results.
The dosage range falls between 5mgs to 30mgs for most types of SARMs so it’s best to start low and work your way up until you hit the optimal range you’re comfortable with. You may also want to try stacking different types of SARMs together if you’re looking for advanced benefits that can’t be found with just one type of SARM.
Can SARMs be stacked for better results?
SARMs are typically taken on their own to achieve certain benefits, but they can also be stacked together for even more advanced benefits that cannot be found with just one type of SARM.
To maximize the positive effects, you’ll need to make sure you’re sticking within your daily dosage limit for each type of SARM you’re taking so you don’t cause yourself any issues.
Just make sure you are always stacking SARMs that are both selective for the same type of receptors so they stack well together to maximize benefits without causing side effects.
What specific types of SARMs exist?
There are dozens of different types of SARMs, but most people will only need to worry about three or four of the most common types.
For example, most people looking for enhanced muscle growth will benefit from using Ostarine (MK 2866), Cardarine (GW 501516), Andarine (S-4), and RAD140 which all provide results through a mechanism known as myostatin inhibition.
In addition to that, people looking for relief from osteoporosis and arthritis typically benefit from using YK11 which works by binding to the androgen receptor to stimulate bone growth.
On top of those two main types, LGD-4033 is a good choice for anyone looking to provide faster wound healing or help increase blood flow.
SARMs proper cycle and PCT
Typically, SARMs are taken for 8-12 weeks and followed up by a post cycle therapy (PCT) plan to help restore your body’s natural testosterone production.
This will take up to 3 months which means you’ll be off of SARMs for 4-6 months before you can start taking them again safely. Make sure you are following the right cycle guidelines to maximize your medication’s benefits.
What are SARMs supplements?
SARM supplements typically contain a combination of natural ingredients that work well with SARMs to enhance their benefits and increase overall results.
For example, some common SARM supplements include:
- Purely Inspired (Ostarine, Andarine, Cardarine)
- EHP Labs (YK11)
- Dymatize Nutrition (LGD-4033)
Are SARMs legal supplements?
SARMs are not legal supplements in a majority of countries around the world because they are considered a controlled substance that is only available by prescription from a doctor.
In most cases, you’ll need to order them online from a website that offers international shipping or get a prescription for your local pharmacy so you can legally use SARMs.
Product reviews for SARMs
- Kent Hunt (February 16, 2021): “SARMs are on the market. It has been shown to be effective in reversing muscle loss, preventing muscle atrophy, and increasing lean mass. I highly recommend SARMs for anyone looking to get an edge on their competition.”
- Billy Jones (March 3, 2021): ” It has helped me recover from a knee injury and I am able to train again without any pain or limitations.”
- Alfred Smith (April 21, 2021): “I have started using SARMs as part of my daily workout routine and I’ve found it to be a great product with little to no side effects.”
- Dylan Lopez (July 19, 2021): “I was skeptical at first but after doing research I decided to try them for myself. They definitely work as advertised and I would recommend them to anyone looking to push their fitness goals a little further.”
- George Cross (August 23, 2021): “My doctor recommended I try using SARMs for my osteoporosis and after trying a few different combinations, I found they worked great and had little to no side effects.”
- Nancy Green (October 4, 2021): “I would recommend any type of SARM but especially YK11 for anyone looking to build bone density and increase blood flow without affecting the prostate or liver.”
- Jeffrey Brown (October 9, 2021): “Be sure to follow a proper cycle and PCT plan as each SARM has different properties that will affect your body differently. Doing so will help you maximize the benefits while minimizing any potential side effects.”
- John Johnson (November 7, 2021): “I’ve heard a lot of good things about SARM supplements and decided to try them for myself. I didn’t experience any side effects and saw great results in terms of lean muscle mass.”
- Samantha Clark (December 29, 2021): “I would recommend using these products with caution especially if you’re at an increased risk for prostate problems. Most of them are mild and won’t cause any serious health concerns but it’s best to stay on the safe side.”
Frequently Asked Questions about SARMs
- How long do SARMs take to work?
- It depends on the product you are taking and its unique chemical properties but in most cases, you’ll be able to see noticeable results after 8-12 weeks of consistent use.
- Are there any side effects when using SARMs?
The short answer is yes, however they are usually mild and can easily be managed by following a proper PCT and cycle plan.
- Do you have to cycle SARMs?
You will need to follow a cycle plan that focuses on gradually increasing the dosage overtime before taking regular breaks from using them, just like when cycling any other supplements.
- What are the best types of SARMs?
There are a lot of different types and brands of SARMs on the market today but some of the most common ones include Ostarine, Andarine, Cardarine, YK11, LGD-4033.
- What is a PCT plan for SARMs?
A post-cycle therapy is a set of supplements and other products that you can use to speed up the process of SARMs detoxification in your body.
- How long should I take a PCT?
You’ll need to follow a proper cycle plan when using any type of SARM product but it will depend on the specific one you are taking. Most are between 6-8 weeks long.
- How do I know what type of PCT to use?
You can read reviews online or consult your doctor about which one would be best to use after taking a cycle of SARMs.
Summary and conclusion
[Conclusion Paragraph]SARMs are a great way to supplement your workout routine and achieve the fitness goals you’ve always wanted. The market is full of different types but it’s best to use one that is designed specifically for your needs. Before taking any SARM supplements, consult with your doctor first and follow all label instructions for best results.
SARMs are completely legal in the U.S. and are known for being mild alternatives to traditional anabolic steroids, offering similar benefits with little to no negative side effects.
They offer many of the same benefits as regular steroids but without any serious health risks or potential complications that you might experience when using other types of supplements.
Most brands are safe for human consumption and have been developed to target specific muscle groups without affecting other parts of the body.
Many professional athletes and fitness enthusiasts have been using them for years with a good amount of success, which has led to their recent surge in popularity among regular people looking to get fit or improve their overall health.
If you’re trying to build more muscles or stay fit, SARMs supplements are a great way to do so and still remain within the confines of your local laws.
You can buy them online or in most fitness and supplement stores and they come highly recommended by professionals and users around the world.